Research progress of the pathogenesis of cholestasis
10.3760/cma.j.issn.1673-4203.2018.10.014
- VernacularTitle:胆汁淤积的发病机制研究进展
- Author:
Fei CAO
1
;
Peng GONG
Author Information
1. 518052,深圳大学总医院普外科
- Keywords:
Cholestasis;
Bile acids and salts;
Pathogenesis
- From:
International Journal of Surgery
2018;45(10):699-703
- CountryChina
- Language:Chinese
-
Abstract:
Cholestasis refers to damage of bile formation or flow at the level of hepatocytes and/or bile duct cells,resulting in the inability of bile to excrete normally into the duodenum and deposit in the liver.Excessive bile acids and bilirubin cause liver cell damage and hepatic fibrosis until liver failure.Therefore,the specific mechanism for the occurrence and development of cholestasis is of great significance for the treatment of the disease and the prognosis of the patient.
