Application advances of carbon nanoparticle in therapy for non-small cell lung cancer

VernacularTitle:纳米碳在非小细胞肺癌治疗中的应用进展
Author: Bin WU ¹ ; Shuai CHEN ; Fangbiao ZHANG ; Hongcan SHI
Author Information

1. 江苏省苏北人民医院胸外科
Keywords: Carbon; Nanotechnology; Carcinoma,non-small-cell lung; Lymph node
From: International Journal of Surgery 2018;45(7):478-481
CountryChina
Language:Chinese
Abstract: Currently,carbon nanoparticle technology is a rapidly developing and emerging technology that has a significant impact in the field of cancer treatment,especially in non-small cell lung cancer.The lymphatic tendency of nano-carbon is used to improve the detection rate of positive lymph nodes,avoiding the leakage of lymph nodes and the crushing and breaking of the lymph nodes to prevent the metastasis of tumorsin non-small cell lung cancer surgery.In addition,carbon nanoparticle has underwent tremendous changes on drug chemical treatment.Its good biocompatibility provides the possibility of serving as a drug carrier,and maintains in vivo drugs at a constant concentration to avoid affecting therapeutic efficacy owning to the half-life of the drug.At the same time,its biological toxicity is lower compared to the traditional drug carrier.This paper focuses on these characteristics of carbon nanoparticle which is applied to the lymphatic target tracking,drug control and release,and elaborates its clinical application prospect in the field of non-small cell lung cancer.