Research progress of gastric cancer circulating tumor cells
10.3760/cma.j.issn.1673-4203.2018.04.014
- VernacularTitle:胃癌循环肿瘤细胞的研究进展
- Author:
Yang OU
1
;
Shuo WANG
;
Kai CUI
;
Sheng LI
;
Dehai GAO
Author Information
1. 250000,济南大学山东省医学科学院医学与生命科学学院
- Keywords:
Stomach neoplasms;
Neoplastic cells,circulating;
Neoplasm metasis;
Detection method
- From:
International Journal of Surgery
2018;45(4):272-276
- CountryChina
- Language:Chinese
-
Abstract:
The incidence of gastric cancer ranks the fourth in all kinds of cancers in the world,ranking the second among patients with cancer-related deaths.The 5-year survival rate of gastric cancer patients is less than 30％.About 50％ of gastric cancer patients have recurred or metastasized after curative resection.Metastasis and recurrence are the major causes of death in cancer patients.CTCs play an important role in tumor metastasis.At present,there are more than 10 kinds of detection methods for CTCs in gastric cancer.The most widely used methods are RT-PCR,FCM,CelLTracks(R) AutoPrep(R) system and ISET.Recent studies have shown that CTCs in peripheral blood of patients with gastric cancer can be used to determine the clinical stage of patients,assess the prognosis and guide the individualized treatment of cancer.
