High-frequency ultrasound blood flow imaging based on laser speckle algorithm
10.3760/cma.j.issn.1673-4181.2018.05.004
- VernacularTitle:基于散斑衬比算法的高频超声血流成像技术研究
- Author:
Liwei WANG
1
;
Shuai LIU
;
Yilu LI
;
Kaining LI
;
Yuejie LI
Author Information
1. 中国医学科学院 北京协和医学院生物医学工程研究所
- Keywords:
High frequency ultrasound;
Laser speckle;
Contrast ratio;
Blood flow imaging
- From:
International Journal of Biomedical Engineering
2018;41(5):390-394
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the application of laser speckle contrast algorithm in high-frequency ultrasound blood flow imaging. Methods The laser speckle contrast algorithm was extended to the field of high-frequency ultrasound blood flow imaging. The high-frequency ultrasound structure images were processed by using the classic laser speckle temporal contrast algorithm to suppress the static tissue signals, enhance the dynamic blood flow signals, and obtain the high-frequency ultrasound blood flow images. The simulation experiments on flow phantoms were conducted to verify the effectiveness of the algorithm, and then human skin tissue in vivo experiments were performed to verify the applicability of the algorithm. The performances of blood flow images which obtained from ultrasound structure images with different frames by laser speckle contrast algorithm were compared and analyzed. Results The blood flow information in a tube was clearly visible in the flow phantoms experiments. The static skin tissue signals were significantly suppressed, dynamic blood flow signals were strengthened in the human skin tissue in vivo experiments, and high-frequency ultrasound blood flow images were obtained. By comparing and analyzing the performances of blood flow images, the results showed that the best blood flow images could be obtained when the number of frame was set to 10 frames. Conclusions The speckle contrast algorithm is feasible and has good application prospects in high-frequency ultrasound blood flow imaging.
