Simulation of flow field characteristics of cyclic variation of human upper respiratory tract
10.3760/cma.j.issn.1673-4181.2018.01.011
- VernacularTitle:人体上呼吸道内压力循环变动的流场特性仿真研究
- Author:
Juan DENG
1
,
2
;
Shuai LIU
;
Fusheng LI
;
Hong SHA
Author Information
1. 300192天津,中国医学科学院北京协和医学院生物医学工程研究所
2. 330031 南昌大学信息工程学院
- Keywords:
Upper respiratory tract;
Cyclic respiratory process;
Instantaneous flow rate;
Cyclic variation of pressure;
Numerical simulation
- From:
International Journal of Biomedical Engineering
2018;41(1):63-71
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the distribution and changes of the upper respiratory tract pressure in the human body under circulatory respiration conditions.Methods An oral-secondary bronchus model was established based on CT images.The pressure distribution at various parts of the model during circulatory respiration and the pressure distribution at the moment of maximum inspiration or expiration were simulated under a respiratory flow of 60 L/min.Results The pressure difference in the upper respiratory tract increased with the respiratory flow.Some positions with special structures,such as pharynx,larynx,trachea,etc.,showed pressure gradient changes,especially between edge of epiglottis to the trachea and upon the bifurcation point of tracheal.Conclusions The air flow motion,including pressure distribution and variation,is related to the anatomy morphological structure of the respiratory tract,and they interactively influence the respiration process.The flow field characteristics of pressure cyclic variation can provide basis for exploring the aerosol deposition and the occurrence and treatment of some respiratory tract diseases.
