Advances in pathogenesis of cerebral small vessel disease
10.3760/cma.j.issn.1673-4165.2018.08.014
- VernacularTitle:脑小血管病发病机制研究进展
- Author:
Jiaojiao JIANG
1
;
Gaiqing YANG
;
Zhiqiang XU
;
Lihong FENG
;
Caixia LI
;
Lixia XU
Author Information
1. 450007,郑州大学附属郑州中心医院神经内科
- Keywords:
Cerebral Small Vessel Diseases;
Endothelium,Vascular;
Oxidative Stress;
Inflammation;
Amyloid β-Peptides;
Blood-Brain Barrier;
Genetic Predisposition to Disease
- From:
International Journal of Cerebrovascular Diseases
2018;26(8):628-631
- CountryChina
- Language:Chinese
-
Abstract:
With the development of imaging, molecular biology, and pathology, the pathogenesis of cerebral small vessel disease (CSVD) has been deeply understood, but the exact pathogenesis is still unclear. This article reviews the pathogenesis of CSVD, including oxidative stress, inflammatory reaction, amyloid beta amyloid deposition, vascular endothelial dysfunction, and blood-brain barrier damage.
