The role of nicotinamide phosphoribosyltransferase in ischemic stroke
10.3760/cma.j.issn.1673-4165.2018.03.014
- VernacularTitle:烟酰胺磷酸核糖基转移酶在脑缺血中的作用
- Author:
Yunxia DUAN
1
;
Di WU
;
Yuchuan DING
;
Xunming JI
Author Information
1. 首都医科大学宣武医院中美神经科学研究所
- Keywords:
Brain Ischemia;
Nicotinamide Phosphoribosyltransferase;
Neuroprotective Agents
- From:
International Journal of Cerebrovascular Diseases
2018;26(3):233-236
- CountryChina
- Language:Chinese
-
Abstract:
At present,there is still no effective drug treatment for acute ischemic stroke except intravenous thrombolysis.Recently,nicotinamide phosphonbosyltransferase (NAMPT) has been found to reduce neurological deficit after cerebral ischemia and reperfusion.This article reviews the neuroprotective effect of NAMPT in ischemic stroke and its potential mechanisms.