Clinical manifestations and imaging features of isolated cortical vein thrombosis:a case series study of 7 cases
10.3760/cma.j.issn.1673-4165.2018.03.006
- VernacularTitle:单纯皮质静脉血栓形成的临床表现和影像学特征:7例病例系列研究
- Author:
Jing REN
1
;
Xiaoyu DONG
;
Qiongyu ZHANG
;
Jianfei XIAN
Author Information
1. 中国医科大学附属盛京医院神经内科
- Keywords:
Venous Thrombosis;
Cerebral Veins;
Cerebral Cortex;
Headache;
Seizures;
Magnetic Resonance Imaging;
Tomography,X-Ray Computed
- From:
International Journal of Cerebrovascular Diseases
2018;26(3):189-194
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical manifestations and imaging features of isolated cortical vein thrombosis (ICoVT).Methods The data of patients with ICoVT admitted and treated in Shengjing Hospital of China Medical University from 2005 to 2015 were collected.Their clinical manifestations and imaging features were analyzed.Results A total of 104 patients with cerebral venous sinus thrombosis were enrolled.Seven (6.7%) of them with ICoVT were enrolled in the analysis.There were 6 women (85.7%).Their average age was 35 years (range 25-46 years).Headache (n =6;85.7%),seizures (n=5;71.4%),and limb paralysis and numbness (n =4;57.1%) were the most common clinical manifestations.All patients underwent head CT,MRI,and magnetic resonance venography (MRV).Focal cerebral tissue edema (n =5;71.4%) and hemorrhagic infarction (n =3;42.9%) were the most common imaging features.Susceptibility weighted imaging of 3 cases revealed cord-like hypointensity,indicating the formation of venous thrombosis.The clinical symptoms of all patients were relieved after anticoagulant therapy.They were followed up for 1.5 years and no recurrence was observed.Conclusion Headache and seizures are the most common clinical symptoms of IcoVT.Imaging is mostly manifested as focal cerebral edema or hemorrhagic infarction.