A case of peripheral T-cell lymphoma with Reed-Sternberg like cells associated with Epstein-Barr virus.
- Author:
Gyu Rak CHON
1
;
Jun Oh JUNG
;
Yun Kwon KIM
;
So Yon KIM
;
Young Jung KIM
;
Min Koo CHO
;
Hyo Jin LEE
Author Information
1. Department of Internal Medicine, National Police Hospital, Seoul, Korea. drsykim@chol.com
- Publication Type:Case Report
- Keywords:
Reed-Sternberg like cells;
Epstein-Barr virus;
Peripheral T-cell lymphoma
- MeSH:
Adult;
Biopsy;
Herpesvirus 4, Human*;
Hodgkin Disease;
Humans;
Infectious Mononucleosis;
Korea;
Lymph Nodes;
Lymphoma, Non-Hodgkin;
Lymphoma, T-Cell, Peripheral*;
Lymphoproliferative Disorders;
Male
- From:Korean Journal of Medicine
2004;67(Suppl 3):S836-S840
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The Reed-Sternberg like cells (RS-like cells) are by no means specific to Hodgkin lymphoma, but they have been reported in various other lymphoproliferative disorders, including infectious mononucleosis. Many studies have postulated that Epstein-Barr virus (EBV) infection may play a role in the development of RS-like cells in non-Hodgkin's lymphoma. There are many accounts in the literature about these RS-like cells in lymph node aspirates and biopsies creating diagnostic confusion with Hodgkin lymphoma, but no report in Korea. We experienced a case of a 44 year-old male patient who had multiple lymph nodes enlargement with the history of treatment of Hodgkin lymphoma 15 years ago. At this time, this patient was diagnosed as peripheral T-cell lymphoma with RS-like cells associated with EBV in lymph node biopsy. Here, we report this case with a review of the relevant literature.
