Risk factors for death within 30 d after acute ischemic stroke
10.3760/cma.j.issn.1673-4165.2017.12.006
- VernacularTitle:急性缺血性卒中发病后30d死亡的危险因素
- Author:
Lin CONG
1
;
Lianqiu MIN
;
Xin YUAN
;
Haitao JIANG
Author Information
1. 123000,阜新市第二人民医院神经内科
- Keywords:
Stroke;
Brain Ischemia;
Survival Rate;
Risk Factors;
Time Factors
- From:
International Journal of Cerebrovascular Diseases
2017;25(12):1089-1095
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the risk factors for death within 30 d after onset in patients with acute ischemic stroke.Methods Consecutive inpatients with acute ischemic stroke were prospectively enrolled.The onset to admission time,baseline clinical characteristics,past history,routine laboratory results,and neuroimaging data of the patients were collected.Taking death within 30 d after the onset as primary outcome,they were divided into a death group and a survival group.The multivariate logistic regression analysis was used to determine the independent risk factors for death.Results A total of 758 patients were enrolled in the study,including 47 (6.2％) deaths.The mortality rate increased gradually with age (P ＜ 0.01).Multivariatelogistic regression analysis showed that male (odds ratio [OR]4.291,95％ confidence interval [CI] 1.560-11.791;P =0.005),age ＞ 80 years (OR 2.440,95％ CI 1.216-4.859;P=0.011),atrial fibrillation (OR 2.394,95％ CI 1.032-5.545;P =0.042),onset to admission time ＞3 h (OR 2.110,95％ CI 1.024-4.350;P =0.043),body temperature ＞37.4 ℃ at admission (OR 2.334,95％ CI 1.122-4.860;P =0.023),oxygen saturation ≤94％ (OR 17.125,95％ CI 2.873-102.162;P =0.001),baseline National Institutes of Health Stroke Scale score ＞ 15 (OR 8.411,95％ CI 2.263-31.287;P =0.003),baseline Glasgow Coma Scale score ＜3 (OR 16.490,95％ CI 2.821-96.444;P =0.005),white blood cell count ＞ 10 × 109/L (OR 2.115,95％ CI 1.042-4.291;P=0.038),complicated with pulmonary infection (OR 8.154,95％ CI 1.818-36.611;P=0.006),and cerebrocardiac syndrome (OR 2.667,95％ CI 1.055-6.740;P =0.038) were the independent risk factors for death within 30 d.Conclusion Male,advanced age,onset to admission time ＞ 3 h,body temperature ＞ 37.4 ℃ at admission,hypoxia,elevated white blood cell cotmt,as well as complicated with pulmonary infection after stroke,and cerebrocardiac syndrome were the independent risk factors for death within 30 d in patients with acute ischemic stroke.
