MicroRNAs and autophagy after cerebral ischemia

VernacularTitle:微小RNA与脑缺血后自噬
Author: Fang HE ^{1
,

2} ; Bin LI ; Wenzhen SHI ; Yu'e YAN ; Xia CHEN ; Lijie GAO ; Nannan HAN ; Huanhuan SHI ; Ning ZHAO ; Xurong ZHU ; Tianzhong WANG ; Ye TIAN
Author Information

1. 710061 西安交通大学
2. 710016 西安市第三医院神经内科
Keywords: Brain Ischemia; Autophagy; MicroRNAs
From: International Journal of Cerebrovascular Diseases 2017;25(11):1053-1056
CountryChina
Language:Chinese
Abstract: MicroRNA is a class of short-chain non-coding RNA that regulates gene expression at post-transcriptional level.It can participate in the pathophysiology processes of tumor regulation,neurodegenerative disease,and cardiovascular disease.Recent studies have shown that microRNA can play a reguhtory role in ischemic brain damage through autophagy.This article reviews the effect of microRNA on autophagy after cerebral ischamia and its possible mechanisms.