Correlation between poststroke depression in acute phase of ischemic stroke and stroke recurrence at 1 year
10.3760/cma.j.issn.1673-4165.2017.11.008
- VernacularTitle:缺血性卒中急性期卒中后抑郁与1年时卒中复发的相关性
- Author:
Ming YANG
1
;
Zuowei DUAN
;
Xinjiang ZHANG
Author Information
1. 扬州市第一人民医院神经内科
- Keywords:
Stroke;
Brain Ischemia;
Depression;
Recurrence;
Risk Factors
- From:
International Journal of Cerebrovascular Diseases
2017;25(11):1009-1012
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the correlation between poststroke depression (PSD) in acute phase of ischemic stroke and stroke recurrence at 1 year.Methods Consecutive patients with acute ischemic stroke were enrolled prospectively.Hamilton Depression Rating Scale and 1 year follow-up were conducted.Multivariate logistic regression was used to identify the independent correlation between stroke recurrence and PSD.Results A total of 331 patients with acute ischemic stroke were enrolled,in which 115 patients (34.7％) with PSD,37 (11.2％) had stroke recurrence in 1 year follow-up period.There were no significant differences in demography and baseline clinical data between the PSD group and the non-PSD group.The age (66.9 ± 11.7 years vs.59.7 ± 11.7 years;t =3.621,P＜0.001),systolic blood pressure (140.0 [133.5-150.0] mmHgvs.135 [127.0-146.0] mmHg;Z=2.302,P=0.021),as well as the proportions of patients with atrial fibrillation (24.3％ vs.9.5％;x2=7.251,P=0.007),diabetes (51.4％ vs.28.6％;x2=7.956,P=0.005) andPSD (17.4％ vs.7.9％;x2=6.852,P=0.009) in the stroke recurrence group were significantly higher than those in the non-recurrent group.Multivariate logistic regression analysis showed that PSD was an independent predictor of stroke recurrence after adjusting for age,systolic blood pressure,total cholesterol,atrial fibrillation,and diabetes (odds ratio 2.15,95％ confidence interval 1.19-5.45;P=0.016).Conclusion PSD in acute phase of ischemic stroke is independently correlated with stroke recurrence at 1 year.
