Risk factors for ischemic stroke complicated with atherosclerotic plaques of lower extremities
10.3760/cma.j.issn.1673-4165.2017.09.005
- VernacularTitle:合并下肢动脉粥样硬化斑块的缺血性卒中的危险因素
- Author:
Zhaochun SHI
1
;
Minyan LU
;
Qingfang HE
;
Chuan HE
;
Yujie YANG
;
Hong ZHOU
;
Zhiqiang QI
;
Hairong DONG
Author Information
1. 210029,南京医科大学第一附属医院神经内科
- Keywords:
Stroke;
Brain Ischemia;
Peripheral Vascular Diseases;
Atherosclerosis;
Lower Extremity;
Ultrasonography,Doppler,Color;
Risk Factors
- From:
International Journal of Cerebrovascular Diseases
2017;25(9):805-808
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the risk factors for acute ischemic stroke in patients with lower extremity atherosclerosis (LEA).Methods The consecutive patients with acute ischemic stroke admitted to hospital within 7 d after onset were enrolled retrospectively.Color Doppler flow imaging was used to detect LEA.The demographic characteristics,vascular risk factors,and laboratory parameters were identified and analyzed.Results A total of 156 patients with acute ischemic stroke were enrolled,including 138 with LEA.Univariate analysis showed that age (69.5± 11.8 years vs.60.4± 11.5 years;t =3.063,P =0.003) and the proportion of patients with hypertension (81.1% vs,55.6%;x2 =2.467,P =0.014) in the LEA group were significantly higher than those in the non-LEA group.Multivariate logistic regression analysis showed that after adjustment for confounders such as gender,baseline systolic blood pressure,diabetes mellitus,and ischemic heart disease,age (odds ratio [OR] 1.059,95% confidence interval [CI] 1.016-1.105;P=0.007),and hypertension (OR 3.128,95% CI 1.084-9.026,P =0.035) were the independent risk factors for acute ischemic stroke complicated with LEA.Conclusions Age and hypertension are associated with acute ischemic stroke complicated with LEA.