Study on the detection value of serum Treg cell related factors and chemokines in patients with tuberculous pleurisy
10.3969/j.issn.1673-4130.2018.11.010
- VernacularTitle:结核性胸膜炎患者血清Treg细胞相关因子及趋化因子的检测价值研究
- Author:
Ya HE
1
;
Shuming TANG
;
Xuecheng WU
Author Information
1. 深圳市人民医院龙华分院检验科
- Keywords:
tuberculous pleurisy;
serum;
T reg cell related factors;
chemokines factors
- From:
International Journal of Laboratory Medicine
2018;39(11):1315-1317,1321
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the value of serum Treg cell related factors and chemokines in patients with tuberculous pleurisy .Methods From July 2015 to December 2016 ,92 cases of tuberculous pleurisy in our hospital were selected as the observation group ,and 92 healthy persons at the same time were selected as the control group .The levels of Treg cell related factors[monocyte chemoattractant protein (MCP)-1 ,IP-10 ,CCL-3 and CCL-16] and IL-10 ,TGF-βand IL-35] were detected and compared in the two groups ,and the levels of these indexes were compared in different classifications and stages of tuberculous pleuritis .Results The ser-um Treg cell related factors and chemokine levels in the observation group were significantly higher than those in the control group (P<0 .05) .The expression level of tuberculous empyema was higher than that of dry pleuritis and exudative pleuritis ,the patients with exudative pleuritis were higher than those of dry pleuritis , and the patients with multiple pleuritis were higher than those with idiopathic and concomitant pleuritis ,the difference was statistically significant (P<0 .05) .Conclusion The serum Treg cell related factors and chemo-kines in patients with tuberculous pleurisy are highly expressed ,and the classification and staging of the dis-ease have great influence on the expression ,and the above indexes have high detection value in the patients with tuberculous pleurisy .
