Study on the level of serum Mullerian inhibiting substance in children with cryptorchidism
10.3969/j.issn.1673-4130.2018.10.018
- VernacularTitle:隐睾患儿血清抗苗勒管激素水平研究
- Author:
Xiaojuan LUO
1
;
Jiaqing LANG
;
Ke CAO
;
Xiaoying FU
;
Fei LI
;
Jianwei LAI
;
Jiahui LI
;
Yunsheng CHEN
;
Dongli MA
Author Information
1. 深圳市儿童医院检验科
- Keywords:
cryptorchidism;
mullerian inhibiting substance;
interstitial cell;
child
- From:
International Journal of Laboratory Medicine
2018;39(10):1224-1226,1229
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the difference of serum levels of anti-Mullenan hormone (AMH) in chil-dren with different ages and different types of cryptorchidism,and to explore its role in the evaluation of tes-ticular development.Methods 60 children with simple cryptorchidism were selected as case group and 52 healthy children were selected as control group.The levels of serum AMH in two groups of children were measured and the differences were compared.Results (1)The level of AMH in the case group was lower than that in control group (P < 0.05),and there was no statistical significance between two subgroups of >6 to 11 years old children with cryptorchidism and healthy children (P>0.05).(2)The level of AMH in bi-lateral cryptorchidism group was lower than that in unilateral cryptorchidism group (P<0.05),and there was no significant difference between two subgroups of >6 to 11 years old children with bilateral cryptorchidism and unilateral cryptorchidism (P>0.05).(3)The level of AMH in the high level cryptorchidism group was lower than that of the low level cryptorchidism group (P<0.05),and there was no statistical difference be-tween between two subgroups of 3~11 year old children with cryptorchidism and low level cryptorchidism (P>0.05).(4)AMH level was negatively correlated with age,and positively correlated with testicular devel-opment.Conclusion AMH can be used as an important indicator of testicular development in children with cryptorchidism.
