Effect of atorvastatin on blood lipid and carotid atherosclerosis in patients with hyperlipidemia and cerebral infarction
10.3969/j.issn.1673-4130.2018.09.011
- VernacularTitle:阿托伐他汀对高脂血症伴脑梗死患者血脂水平、颈动脉粥样硬化情况的影响及分析
- Author:
Zedong SANG
1
;
Shuyong GE
;
Yu LI
;
Liangjun HE
;
Qingyin WANG
;
Manping CHEN
Author Information
1. 滁州市第一人民医院神经内科
- Keywords:
atorvastatin;
hyperlipidemia;
cerebral infarction;
blood lipid;
carotid atherosclerosis
- From:
International Journal of Laboratory Medicine
2018;39(9):1062-1064
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of atorvastatin on blood lipid and carotid atherosclerosis in patients with hyperlipidemia and cerebral infarction.Methods 98 patients with hyperlipidemia and cerebral in-farction in our hospital from September 2014 to February 2017 were selected and divided into observation group(49 cases)and control group(49 cases)according to the random number table method.The control group was treated with conventional treatment,the observation group was treated with atorvastatin on the ba-sis of the control group.The two groups were treated for 4 weeks.The ADL score,NIHSS score,blood lipid index,carotid IM T and carotid plaque area were compared between the two groups before and after treatment. Results ADL score of the patients in the observation group after treatment higher was than the control group (t=12.7783,P<0.05),NIHSS score was lower than the control group(t=10.941,P<0.05);LDL-C,TC and TG levels after treatment in the observation group were than in the control group(t= 17.239,9.216, 9.800,P<0.05),while the HDL-C level was higher than the control group(t=7.683.P<0.05);the patients in the observation group were treated by carotid artery IM T and carotid plaque area was higher than that of the control group(t=8.919,6.344,P<0.05).Conclusion Atorvastatin can improve hyperlipidemia in pa-tients with cerebral infarction and carotid atherosclerosis,dyslipidemia,has the important research signifi-cance.
