Correlation analysis of high sensitivity C reactive protein,homocysteine, interleukin 2 and lipoprotein associated phospholipase A 2 and coronary heart disease
10.3969/j.issn.1673-4130.2018.07.019
- VernacularTitle:hs-CRP、Hcy、IL-2和Lp-PLA2与冠心病的相关性研究
- Author:
Yongjiang CAI
1
;
Danjun WANG
;
Linlin LU
;
Xiaohong CHEN
Author Information
1. 北京大学深圳医院体检科
- Keywords:
high sensitivity C reactive protein;
homocysteine;
interleukin 2;
lipoprotein associated phospholipase A2;
coronary heart disease
- From:
International Journal of Laboratory Medicine
2018;39(7):831-833
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the high sensitive C reactive protein(hs-CRP),homocysteine(Hcy), interleukin 2(IL-2)and lipoprotein associated phospholipase A 2(Lp-PLA2)analysis and correlation test for coronary heart disease.Methods 147 cases were selected from our hospital in December 2015 to December 2016 in patients with coronary heart disease(observation group).At the same time,we selected 51 healthy persons in our hospital during December 2015 to December 2016 as control group.The content of hs-CRP was determined by immune transmission turbidimetry.The content of Hcy was determined by cyclic enzymatic method.The content of IL-2 was determined by enzyme linked immunosorbent assay(ELISA).The content of Lp-PLA2 was determined by immune transmission turbidimetry.Results The observation group serum levels of hs-CRP,Hcy,IL-2 and Lp-PLA2 were significantly higher than those in the control group,and the differ-ence were statistically significant(P<0.05).The coronary heart disease each group serum levels of hs-CRP, Hcy,IL-2 and Lp-PLA2 were significantly higher than those in the control group,and the differences were sta-tistically significant(P<0.05).The serum levels of hs-CRP,Hcy,IL-2 and Lp-PLA2 of AMI group were sig-nificantly higher than those in UAP group and SAP group,and the differences were statistically significant (P<0.05).The UAP group serum levels of hs-CRP,Hcy,IL-2 and Lp-PLA2 were significantly higher than those in SAP group,and the difference was statistically significant(P<0.05).Conclusion Hs-CRP,Hcy,IL-2,Lp-PLA2 have significant correlation with coronary heart disease.
