Distribution and change of the pathogens and multi-drug resistant organisms in intensive care unit during 6 years
10.3969/j.issn.1673-4130.2018.07.017
- VernacularTitle:广东某院重症监护病房病原菌及多重耐药菌的分布和变迁
- Author:
Yuanchun HUANG
1
;
Suqin HAN
;
Zhuoran CHEN
;
Fang JIANG
;
Chun LIN
;
Jun LIU
;
Maozhang FU
;
Yongfeng XU
Author Information
1. 汕头大学医学院第一附属医院检验科
- Keywords:
intensive care unit;
pathogen;
multi-drug resistant organism
- From:
International Journal of Laboratory Medicine
2018;39(7):824-827
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the distribution and changes of pathogens in intensive care unit of our hospital from 2010 to 2015,and provide treatment suggestions for infection.Methods The data of pathogens and multi-drug resistant organisms(MDROs)in ICU from 2010 to 2015 were analyzed retrospectively by WHONET5.6,Microsoft Office Excel2007 and SPSS19.0.Results The numbers of pathogens in ICU were increasing year by year while the top six were Acinetobacter baumanni,Pseudomonas aeruginosa,Klebsiella pneumoniae,Escherichia coli,Staphylococcus aureus and Candida albicans.The dominant MDROs were multi-drug resistant Acinetobacter baumanni,multi-drug resistant Pseudomonas aeruginosa,extended spectrum β lactamase producing Escherichia coli and Klebsiella pneumonia,methicillin-resistant coagulase negative Staph-ylococcus and methicillin-resistant Staphylococcus aureus,etc.There were statistically dramatic significant differences of most MDROs during the six years(P<0.01).Conclusion The pathogens of ICU were mainly bacteria related to the healthcare associated infection,and the multi-drug resistance was obviously in dynamic change as well as most pathogens.As a suggestion,antibiotic agents should be used rationally according to the antimicrobial susceptibility results for treating the MDROs.
