The relationship between PCT,CRP and BNP levels in peripheral blood of patients with sepsis and cTn I and its clinical significance
10.3969/j.issn.1673-4130.2018.07.013
- VernacularTitle:脓毒症患者外周血PCT、CRP、BNP水平与cTnI的关系
- Author:
Guilan PAN
1
;
Chunhong HUANG
;
Changshao ZHOU
Author Information
1. 中国人民解放军第九五医院检验科
- Keywords:
procalcitonin;
C reactive protein;
type B brain natriuretic peptide;
troponin I
- From:
International Journal of Laboratory Medicine
2018;39(7):812-814
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relationship between serum PCT,CRP,BNP and cardiac troponin I (cTnI)and its clinical significance in patients with sepsis.Methods 112 patients with sepsis treated in our hospital were collected.Patients were divided into sepsis,severe sepsis and septic shock groups according to their degree of illness.The serum levels of cTnI and cTnI were measured in peripheral blood samples of pa-tients with sepsis,severe sepsis and sepsis shock.To analyze the correlation between serum cTnI and cTn I in patients with sepsis.The levels of BNP and cTnI were significantly higher in septic shock group than in severe sepsis group.The difference was statistically significant(P<0.01),and that in severe sepsis group was signif-icantly higher than that in sepsis group(P<0.01).The results of correlation analysis showed that there was a positive correlation between serum PCT,BNP,CRP and cTnI levels,but the correlation was PCT(r =0.831)>BNP(r=0.456)>CRP(r=0.287).Results Conclusion cTnI and serum PCT,CRP,BNP are in the serum of the patients.With the exacerbation of sepsis patients,there will be more significant myocardial injury symptoms.