Expression and clinical significance of serum ICAM-1,sICAM-1 and hs-CRP in patients with plasma cell mastitis
10.3969/j.issn.1673-4130.2018.06.006
- VernacularTitle:血清ICAM-1、sICAM-1、hs-CRP在浆细胞性乳腺炎中的表达及临床意义
- Author:
Yong SUN
1
;
Yuwen TONG
;
Haiyan XU
;
Shuyan WANG
Author Information
1. 山东省枣庄市妇幼保健院乳腺外科
- Keywords:
plasma cell mastitis;
intercellular adhesion molecule-1;
soluble intercellular adhesion mole-cule-1;
high sensitive C-reactive protein
- From:
International Journal of Laboratory Medicine
2018;39(6):658-660
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the expression and clinical significance of serum intercellular adhesion molecule-1(ICAM-1),soluble intercellular adhesion molecule-1(sICAM-1)and high sensitive C-reactive pro-tein(hs-CRP)in the patients with plasma cell mastitis(PCM).Methods 45 cases of PCM and 45 persons un-dergoing healthy physical examination in the Zaozhuang Municipal Maternal and Child Health Care Hospital from August 2015 to February 2017 were selected and served as the PCM group and control group.The ex-pression levels of serum CAM-1,sICAM-1 and hs-CRP were detected in the two groups.Then the results were statistically analyzed.Results The vascular endothelial cell ICAM-1 level in the PCM group was slightly low-er than that in the control group,while the ductal endothelial cell ICAM-1 level was higher than that in the control group,the difference was statistically significant(P<0.05);the levels of serum sICAM-1 and hs-CRP levels in the PCM group were significantly higher than those in the control group,the difference was statisti-cally significant(P<0.05).The ductal endothelial cell ICAM-1,sICAM-1 and hs-CRP levels after treatment in the PCM group were significantly lower than those before treatment,the difference was statistically significant (P<0.05).Conclusion The expression of serum ICAM-1,sICAM-1 and hs-CRP is closely correlated with PCM disease,can serve as the effective indicators for its clinical judgment and is worth promotion and applica-tion.
