Evaluation of diagnostic value of PTH in chronic renal failure by ROC curve
10.3969/j.issn.1673-4130.2018.06.002
- VernacularTitle:应用ROC曲线评价PTH对慢性肾衰竭的诊断价值
- Author:
Juan ZHAO
1
;
Yinzhong YANG
;
Jianying ZHANG
Author Information
1. 四川省医学科学院/四川省人民医院城东病区检验科
- Keywords:
parathyroid hormone;
chronic renal failure;
receiver operating characteristic value
- From:
International Journal of Laboratory Medicine
2018;39(6):645-647
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the clinical diagnostic value of parathyroid hormone(PT H)in the diagno-sis of chronic renal failure(CRF).Methods 162 cases of CRF patients who were treated in the Sichuan Pro-vincial People′s Hospital from January 2014 to October 2015 were selected as the CRF group,meanwhile 164 non-CRF(NCRF)patients and 167 persons undergoing healthy physical examination were selected as the NCRF group and the healthy control group respectively.The PTH level was detected in 3 groups.According to the detection results the receiver operating characteristic(ROC)curve was drawn,and the diagnostic value of PTH for CRF was evaluate.Results The PTH level in the CRF group was significantly higher than that in the NCRF group and healthy control group,the difference was statistically significant(P<0.05);when the di-agnostic cut off value of PT H for CRF was 75.00 nmol/L,the area under the ROC curve,sensitivity,specifici-ty,positive likelihood ratio and Youden index were 0.92,80.20%,97.80%,36.45 and 78.00 respectively.Con-clusion PT H has a good diagnostic value to CRF.With the cut off value of PT H for diagnosing CRF as 75.0 nmol/L,it can improve the efficiency of clinical diagnosis.
