The study of application of thrombus elastograph in evaluating coagulation function of patients with acute ischemic stroke
10.3969/j.issn.1673-4130.2018.05.016
- VernacularTitle:血栓弹力图在评价急性缺血性卒中患者凝血功能中的应用研究
- Author:
Li WEI
1
;
Yilin YANG
;
Ya PENG
;
Peng ZHOU
;
Chenhong QU
Author Information
1. 常州市第一人民医院输血科
- Keywords:
thrombelastogram;
acute cerebral infarction;
blood coagulation function
- From:
International Journal of Laboratory Medicine
2018;39(5):573-576
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the role of thrombus elastograph (TEG) in evaluating the coagulation function of patients with acute ischemic stroke.Methods Totally 116 cases of patients with acute ischemic stroke and 116 cases of health physical examination people from our hospital were selected as case group and control group.The blood clotting index and thrombelastogram index of the groups were detected.Results In case group of acute phase,fibrinogen (FIB),two D-dimer (D-D),maximum blood clot strength (MA),0.5 h blood clot reduction rate of MA (LY30),alpha angle,integrated coagulation index (CI) and blood clot strength (G) were significantly higher than those of control group and the recovery period group.The difference was statistically significant(P＜0.01).In cases of acute phase,activated partial thromboplastin time (APTT),prothrombin time (PT),PT-INR,reaction time (R),clot formation time (K value) were significantly lower than those in the healthy control group and the recovery period cases,the difference was statistically significant (P＜0.01).MA,LY30,α Angle and CI were negatively correlated with PT,APTT,PT-INR,and were positively correlated with FIB,D-D(P＜0.05);R value,K value were positively correlated with PT,APTT,PT-INR,and were negatively correlated with FIB,D-D(P＜ 0.05).Conclusion TEG plays a significant role in monitoring and evaluating coagulation function in patients with acute ischemic stroke,and has important evaluation effect on the prognosis of disease.It is worthy of clinical application.
