Systematic evaluation on the diagnostic role of red blood cell distribution width in iron deficiency anemia
10.3969/j.issn.1673-4130.2018.05.015
- VernacularTitle:系统性评价红细胞分布宽度在缺铁性贫血诊断中的价值
- Author:
Longmei CHEN
1
;
Wanchao LIU
;
Wenhui WANG
;
Zhenhua YANG
Author Information
1. 上海市宝山区中西医结合医院检验科
- Keywords:
iron deficiency anemia;
red index;
diagnosis;
Meta analysis
- From:
International Journal of Laboratory Medicine
2018;39(5):570-572,576
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the value of red blood cell distribution width (RDW) in the diagnosis of Iron Deficiency Anemia(IDA).Methods Most relevant studies,which were retrieved from the Medline,Embase,and the Cochrane Library were identified according to the inclusion and exclusion criteria and data were extracted.Statistical analyses were performed by employing Meta-DiSc 1.4 software.Meta-analysis of the reported accuracy of each study was performed and summary receiver operating characteristic (SROC) curve was drawn.Results Four studies met the inclusion criteria for the analysis.Heterogeneity test did not find significant heterogeneity among included studies.RDW＞14％ was taken as the diagnostic critical value,the sensitivity was 0.92[95％CI(0.88,0.94)],the specificity was 0.41[95％CI(0.35,0.47)] and the AUC of SROC was 0.87.Conclusion RDW is sensitive and has good value in the diagnosis of IDA.
