Progress in the treatment of steroid-sensitive, steroid-dependent, and frequently relapsing nephrotic syn-drome in children
10.3760/cma.j.issn.1673-4408.2018.10.002
- VernacularTitle:儿童激素敏感、依赖和频复发性肾病综合征的治疗进展
- Author:
Fan YANG
1
;
Jiong DENG
Author Information
1. 中山大学附属第一医院儿科
- Keywords:
Nephrotic syndrome;
Children;
Glucocorticosteroid;
Immunosuppressive agents
- From:
International Journal of Pediatrics
2018;45(10):747-751
- CountryChina
- Language:Chinese
-
Abstract:
Primary nephrotic syndrome( PNS) is a common kidney disease in children. Glucocorticoste-roid( GC) is recognized as the first-line drug,and most children are sensitive to it. However,the problems of fre-quent relapses and steroid-dependence still have not been solved. In recent years,a number of randomized con-trolled studies have been conducted on the dosage of GC medications,the efficacy and safety of immunosuppres-sive agents,some of which try to figure out how to effectively reduce relapse and the rate of hormone-depend-ence. This review summarizes the progress in the treatment of steroid-sensitive,steroid-dependent,and frequently relapsing nephrotic syndrome.
