Rho kinase signal pathway and inflammatory bowel disease
10.3760/cma.j.issn.1673-4408.2018.09.012
- VernacularTitle:Rho/ROCK信号通路与炎症性肠病
- Author:
Xiaoting SHEN
1
Author Information
1. 浙江大学医学院附属儿童医院消化科
- Keywords:
Inflammatory bowel disease;
Crohn disease;
Ulcerative colitis;
Rho kinase
- From:
International Journal of Pediatrics
2018;45(9):697-700
- CountryChina
- Language:Chinese
-
Abstract:
Rho/Rho-kinase signaling pathway is a ubiquitous one in vivo and plays a role of "molecular switch" by regulating the polymeric state of intracellular actin cytoskeleton and participates in the regulation of various cellular functions.As research continues,some of them have provided evidence of Rho kinase signal pathway function at the occurrence and development of inflammatory bowel disease.This review aims to summarize the relationship between Rho kinase signal pathway and inflammatory bowel disease.
