Analysis of pathogenic characteristics and drug resistance of urine culture in children
10.3760/cma.j.issn.1673-4408.2018.06.013
- VernacularTitle:儿童尿培养的病原学特点及耐药性分析
- Author:
Dongmei YUE
1
;
Jiahe WANG
;
Yajie TONG
;
Fan YANG
Author Information
1. 中国医科大学附属盛京医院儿科
- Keywords:
Children;
Urine culture;
Pathogenic bacteria;
Drug resistance
- From:
International Journal of Pediatrics
2018;45(6):465-469
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the distribution of pathogenic bacteria characteristics and antimicrobial susceptibility results in children with positive urine culture specimen in order to provide some references for the clinical rational use of antimicrobial agents.Methods The pathogenic data of children in our hospital in 2017 with positive urine culture specimen were collected and statistical analyzed.Results A total of 364 strains of 23 pathogens have been isolated,which the Escherichia coli was dominant,accounting for 41.21％ (150strains).followed by Enterococcus faecium (18.41％),Klebsiella pneumoniae (14.29％) and Enterococcus faecalis (7.15％).Different pathogenic bacterias have varying degrees of drug resistance to commonly used antibiotics.The drug resistance rates of Escherichia coli to ampicillin,piperacillin,cefmenorr and cefazolin were 88.36％,85.71％,81.58％ and 81.16％.The drug resistance rates of Enterococcus faecium to ampicillin,clindamycin and penicillin G were 100％;the drug resistance rates of Klebsiella pneumoniae to ampicillin,tetracycline,cefazolin and cefuroxime axetil were 96.08％,92.31％,82.98％ and 80％;All Enterococcus faecalis detected were sensitive to qulnupristin/dalfopristin and clindamycin.Conclusion Escherichia coil,Enterococcus faecium,Klebsiella pneumoniae and Enterococcus faecalis ate common pathogens in positive urine culture of children.Clinicians should use antibiotics reasonably according to the pathogenic characteristics.
