Progresses in genetics of coronary artery lesion in Kawasaki disease
10.3760/cma.j.issn.1673-4408.2018.05.001
- VernacularTitle:川崎病冠状动脉病变的遗传学研究进展
- Author:
Zhengshan ZHAO
1
Author Information
1. 复旦大学附属儿科医院心内科
- Keywords:
Kawasaki disease;
Coronary artery lesion;
Gene polymorphism
- From:
International Journal of Pediatrics
2018;45(5):329-332
- CountryChina
- Language:Chinese
-
Abstract:
Kawasaki disease (KD)also known as mucocutaneous lymph node syndrome is a systemic vascular disease without clear etiology.KD mainly occurs in infants and children under the age of five.Coronary artery lesion(CAL) is the most important factor affecting the prognosis of KD patients.It is the main cause of childhood ischemic heart disease,including coronary artery dilatation,coronary aneurysm and coronary artery stenosis.So far,more and more researches indicate that genetic factors play a significant role in the pathogenesis of KD with coronary artery injury.This article focuses on the progress of gene polymorphism in KD with coronary artery injury.
