The interaction between monoaminergic system and hypothalamic-pituitary-adrenal axis
10.3760/cma.j.issn.1673-4408.2018.03.009
- VernacularTitle:单胺能系统与HPA轴在注意缺陷多动障碍中的交互作用
- Author:
Hongzhu LU
1
Author Information
1. 福建医科大学附属协和医院儿科
- Keywords:
Attention deficit hyperactivity disorder;
Monoaminergic system;
Hypothalamic-pituitary-adrenal axis;
Transcription factor
- From:
International Journal of Pediatrics
2018;45(3):192-195
- CountryChina
- Language:Chinese
-
Abstract:
Attention deficit hyperactivity disorder (ADHD) is one of the common neurodevelopmental disorders in childhood characterized by inattention,hyperactivity,impulsivity,cognitive impairment and learning difficulties and has a negative effect on children.The specific pathogenesis of ADHD is not fully clear.Recent studies have found that there are interactions between monoaminergic system and hypothalamic-pituitary-adrenal axis,in which the machanism is associated with transcription factors,such as Spl、KLF11、R1.This article reviews the characteristics of the monoaminergic system and hypothalamic-pituitary-adrenal axis in attention deficit hyperactivity disorder,and the machanism with transcription factors.
