The pathogenesis of acute lung injury and the treatment effect of mesenchymal stem cells
10.3760/cma.j.issn.1673-4408.2018.01.012
- VernacularTitle:急性肺损伤的发病机制及间充质干细胞治疗作用的研究进展
- Author:
Qianying LI
1
Author Information
1. 中国医科大学附属盛京医院PICU
- Keywords:
Acute lung injury;
Mesenchymal stem cell
- From:
International Journal of Pediatrics
2018;45(1):44-47
- CountryChina
- Language:Chinese
-
Abstract:
Acute lung injury and acute respiratory distress syndrome are characterized by acute,progressive dyspnea,refractory hypoxemia and bilateral pulmonary innfiltrates.Stem cell is a type of cell with strong differentiation function,which can differentiate into various types of cells,such as endothelial cells,epithelial cells,adipocytes and chondrocytes.The therapeutic potential and safety of mesenchymal stem cells (MSCs) in regenerative therapy and immune regulation have become the research hotspot.A large number of studies have shown that MSC can be used to treat lung injury in many ways,but the specific mechanism is not clear.Therefore,the mechanism of acute lung injury and the therapeutic effects of marrow MSC in acute lung injury will be reviewed in this paper.
