Calcitonin gene-related peptide and lung diseases
10.3760/cma.j.issn.1673-4408.2017.12.002
- VernacularTitle:降钙素基因相关肽与肺部疾病
- Author:
Hongmin FU
1
;
Yan GONG
Author Information
1. 650034,昆明市儿童医院云南省儿科研究所
- Keywords:
Calcitonin gene-related peptide;
Lung;
Diseases
- From:
International Journal of Pediatrics
2017;44(12):818-821
- CountryChina
- Language:Chinese
-
Abstract:
Pulmonary diseases include infection,injury,asthma,interstitial disease,tumor,hypertension and so on.The mechanisms are not fully understood.Calcitonin gene-related peptide(CGRP),a 37-amino acid neuropeptide,identified in multiple species,has widespread distribution and expression.Although there are no cases that CGRP works in pulmonary disease,many studies have showed that CGRP play an important role on cell line in vitro or on animal models.This brief review provides a preliminary understanding of the diverse biological effects of CGRP and its antagonist in respiratory system.
