Efficiency Analysis of EX16+10Y Kit on Detection of the Uygur Population in Xinjiang Province
10.3969/j.issn.1004-5619.2018.02.010
- VernacularTitle:EX16+10Y试剂盒检测新疆维吾尔族人群的效能
- Author:
Gang BI
1
;
Chen ZHANG
;
Yan DONG
;
Hai-Tao JIAO
;
Lei DONG
;
Huai-Gu ZHOU
Author Information
1. 上海市公安局物证鉴定中心 法医物证学现场应用技术公安部重点实验室 上海市现场物证重点实验室
- Keywords:
forensic genetics;
Y chromosome;
short tandem repeat;
EX16+10Y kit;
Xinjiang;
Uygur na-tionality
- From:
Journal of Forensic Medicine
2018;34(2):154-156,160
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyse the efficiency of EX16+10Y kit on the forensic detection of the Uygur in Xinjiang province. Methods The blood samples were extracted from 4620 male individuals of Uygur in Xinjiang province, and amplified by EX16+10Y kit. The typing of amplification products was per-formed by 3130xl genetic analyzer. Results The genotyping graphs of 15 autosomal STR loci and 10 Y-chromosomal STR loci from 4620 male individuals of Uygur in Xinjiang province were acquired completely. The genotype distribution of 15 autosomal STR loci was consistent with Hardy-Weinberg equilibrium. The heterozygosity, polymorphism information content and discrimination power of STR loci were 0.637-0.838, 0.580-0.860 and 0.811-0.978, respectively. There were 766 haplotypes in 10 Y -chro-mosomal STR loci. Conclusion The test results of EX16+10Y kit is accurate and trustworthy, which can simultaneously be used for the individual identification and the screening of paternal pedigree in practical work.
