Relationship between Myofibril Fragmentation Index and Postmortem Interval
10.3969/j.issn.1004-5619.2017.06.004
- VernacularTitle:肌原纤维小片化指数与人体死亡时间的相关性
- Author:
Li SHEN
1
;
Rui-Zhong YUAN
;
Jie BIAN
;
Meng HE
;
Zi-Qin ZHAO
Author Information
1. 银川市公安局物证鉴定所
- Keywords:
forensic pathology;
muscle;
skeletal;
myofibril fragmentation index;
postmortem interval
- From:Journal of Forensic Medicine
2017;33(6):592-594
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the relationship between myofibril fragmentation index (MFI) of human skeletal muscle and postmortem interval (PMI). Methods The protein concentrations of human right bi-ceps brachii muscle and right quadriceps femoris muscle were obtained at different PMI, and detected at room temperature by biuret method. The MFI of skeletal muscle at 540 nm was measured by ultraviolet spectrophotometer. Regression analysis was performed with time of death as independent variable (x) and MFI as dependent variable (y). Results In early PMI, the MFI of human skeletal muscle increased obviously according to the prolongation of PMI, and peaking by 12 h and then tended to steady. Within 12 h after death, the regression equations of right biceps brachii muscle and right quadriceps femoris muscle were y=32.660+3.227 x(r=0.9879) and y=32.380+3.495 x(r=0.9839), respectively. Conclusion There's high correlation between MFI and PMI. Combining with forensic practice, MFI can be used for the estimation of early PMI (especially in 12 h).
