Fast Analysis of Veterinary Drugs in Feed Using Gold Nanoparticles-assisted Dielectric Barrier Discharge Ion Source-Mass Spectrometry
10.11895/j.issn.0253-3820.181099
- VernacularTitle:纳米金辅助介质阻挡放电离子化质谱分析法在兽药饲料快检中的应用
- Author:
Peng ZHAO
1
;
Yun LIU
;
Huan-Huan HONG
;
Lu-Hong WEN
;
Zhen-Zhi SHI
;
Xin-Rong ZHANG
;
Si-Chun ZHANG
;
Xue-Jun LI
Author Information
1. 宁波大学高等技术研究院
- Keywords:
Dielectric barrier discharge ion source-mass spectrometry;
Paper-based injection;
Gold nanoparticles;
Veterinary drug
- From:
Chinese Journal of Analytical Chemistry
2018;46(7):1089-1094
- CountryChina
- Language:Chinese
-
Abstract:
Dielectric barrier discharge ion source-mass spectrometry ( DBDI-MS) can achieve in-situ and efficient detection of samples without tedious pretreatment, and has become a popular analytical method. To improve the detection sensitivity, a novel mass spectrometric method based on gold nanoparticles ( AuNPs)-assisted paper-based injection mode and DBDI-MS technology was developed for the fast determination of four veterinary drugs. The detection signal strength was improved by 8-31 times compared to the veterinary drugs which were tested without AuNPs-assisted paper based injection. Under the optimal conditions, the experimental data of four veterinary drugs showed a good linear relationship between the signal and the concentration in the respective range, with correlation coefficient ( r ) of 0. 951-0. 996. Moreover, the recoveries were between 79. 4% and 96. 5% at three spiked levels. This method has many distinct advantages, such as low detected limitation, low cost and high efficiency, and is also very suitable for fast on-site detecting, showing great potential in feed quality control.
