Progress in Solid-state Nanopore-based Analysis Technology
10.11895/j.issn.0253-3820.181217
- VernacularTitle:固体纳米孔分析技术的研究进展
- Author:
Zhi LI
1
;
Li-Ping LIU
;
Zhen FANG
;
Dong-Mei XI
Author Information
1. 临沂大学化学化工学院
- Keywords:
Solid nanopore;
Single-molecule analysis;
DNA sequencing;
Review
- From:
Chinese Journal of Analytical Chemistry
2018;46(6):836-842
- CountryChina
- Language:Chinese
-
Abstract:
Nanopore technique is a low-cost tool for single-molecule level analysis without the need of label or amplification. The solid nanopores have been widely used in many fields such as chemistry and life sciences due to their advantages such as high stability, good tolerability, controllable size, and easy for modification. The solid nanopores commonly used in recent years are fabricated using two types of materials: membrane and tube. The membrane materials include silicon nitride, two-dimensional materials, aluminium oxide, and polymer membranes. The tube materials mainly include glass capillary and carbon nanotube. This review summarizes and prospects the research progress of different solid nanopores.
