Diagnostic value of Eos in nasal secretion of allergic rhinitis patients to predict serum slgE level
10.16066/j.1672-7002.2018.02.009
- VernacularTitle:变应性鼻炎鼻分泌物嗜酸性粒细胞预测血清特异性IgE的诊断价值
- Author:
Jingli XU
1
;
Jienan XIA
;
Jingyi ZHAO
;
Baoxia SUN
;
Liying SHAN
;
Haifang TIAN
;
Yajuan ZHAO
;
Junge WANG
Author Information
1. 北京中医医院顺义医院耳鼻咽喉科
- Keywords:
Rhinitis,Allergic,Perennial;
Eosinophils;
Immunoglobulin E;
nasal secretions smear
- From:
Chinese Archives of Otolaryngology-Head and Neck Surgery
2018;25(2):89-92
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To investigate the relationship between the distribution of eosinophils(Eos) of nasal secretion and serum specific IgE(sIgE) titer in patients with allergic rhinitis, and to evaluate the diagnostic value of Eos in nasal secretion for allergic rhinitis. METHODS A total of 60 allergic rhinitis patients from Department of Otolaryngology, Beijing Shunyi Hospital of Traditional Chinese Medicine during Jan.2016 to June 2017 were selected as treatment group, and another 60 cases of non-allergic rhinitis and 30 normal persons in the corresponding time period were chosen as control group. Eos in nasal secretions and serum sIgE were measured in all the subjects and the relationship between Eos distribution and serum sIgE level was analyzed. RESULTS The Eos distribution and serum level of sIgE was consistent(κ=0.264, P=0.000) and statistical significance was found. The area of ROC of the Eos in nasal secretion was 0.881, the standard deviation was 0.025 and 95％ confidence interval was 0.841 to 0.924. The Udden index of ROC reached the maximum when the Eos in nasal secretion smear was graded as level 3, the sensitivity was 88.5％ and specificity was 99.4％. CONCLUSION Eos cytological examination of nasal secretions has some auxiliary value in the diagnosis of allergic rhinitis. It is a cheap, simple and rapid method, which can be used as an effective reference index for diagnosing allergic rhinitis in primary hospital.
