Distinct Clinical Characteristics of Unplanned Excision in Synovial Sarcoma.
10.4055/cios.2015.7.2.254
- Author:
Eun Seok CHOI
1
;
Ilkyu HAN
;
Hwan Seong CHO
;
Hyun Guy KANG
;
June Hyuk KIM
;
Han Soo KIM
Author Information
1. Department of Orthopedic Surgery, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea. hankim@snu.ac.kr
- Publication Type:Clinical Study ; Original Article
- Keywords:
Synovial sarcoma;
Oncologic outcomes;
Magnetic resonance imaging
- MeSH:
Adolescent;
Adult;
Aged;
Aged, 80 and over;
Child;
Child, Preschool;
Female;
Humans;
Male;
Middle Aged;
Retrospective Studies;
Sarcoma, Synovial/*diagnosis/*surgery;
Soft Tissue Neoplasms/*diagnosis/*surgery;
Treatment Outcome;
Young Adult
- From:Clinics in Orthopedic Surgery
2015;7(2):254-260
- CountryRepublic of Korea
- Language:English
-
Abstract:
BACKGROUND: We aimed to describe the clinical characteristics and outcomes of unplanned excisions of synovial sarcomas. METHODS: In total, 90 patients with synovial sarcomas in the extremities were retrospectively reviewed. Patients were divided into unplanned excision (n = 38) and planned excision (n = 52) groups. The average follow-up period was 6 years. The clinicopathological characteristics and oncologic outcomes were compared. RESULTS: The unplanned excision group showed longer duration of symptoms before diagnosis (p = 0.023), smaller lesion dimensions (p = 0.001), superficial location (p = 0.049), and predilection in the upper extremities (p = 0.037). Synovial sarcomas were most commonly misdiagnosed as neurogenic tumors (56%) in the upper extremities or as cystic masses (47%) in the lower extremities. Oncological outcomes, including disease-specific survival, metastasis-free survival, or local recurrence were not significantly different between the 2 groups (p = 0.159, p = 0.444, and p = 0.335, respectively). Repeated unplanned excision (p = 0.012) and delayed re-excision (p = 0.038) were significant risk factors for local recurrence in the unplanned excision group. CONCLUSIONS: Synovial sarcomas treated with unplanned excision had distinct characteristics. These findings are important for developing diagnostic and therapeutic strategies for synovial sarcoma.
