The effect of early enteral nutrition on ventilator associated pneumonia in patients with Guillain Barre syndrome
10.16151/j.1007-810x.2018.01.006
- VernacularTitle:早期肠内营养对吉兰-巴雷综合征病人呼吸机相关性肺炎的影响
- Author:
Xin JIN
1
;
Ying SHI
;
De-Chao WANG
;
Hai-Yan LIU
;
Hui-Ling WANG
;
Wei-Bin LI
;
Kai WANG
;
Ran DING
Author Information
1. 河北大学附属医院神经内科,河北保定071000
- Keywords:
Early enteral nutrition;
Hospital acquired pneumonia;
Ventilator associated pneumonia;
Guillain-Barre syndrome
- From:
Parenteral & Enteral Nutrition
2018;25(1):16-19,23
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the effect of early enteral nutrition on ventilator-associated pneumonia in patients with Guillain Barre syndrome.Methods:This study was a prospective study.The study subjects were 36 patients diagnosed with Guillain Barre syndrome in the neuro-intensive care unit of our hospital from May 2011 to May 2017.Among them,18 patients received enteral nutrition support treatment within 24 hours after mechanical ventilation (early group),and 18 patients received enteral nutrition support treatment more than 24 hours after mechanical ventilation (control group).The two groups were compared with nutritional indicators,complications of enteral nutrition,ventilatorassociated pneumonia incidence,mechanical ventilation time,NICU residence time,APACHE Ⅱ score and mortality after treatment.Results:In the early group,the incidence of ventilator-associated pneumonia,mechanical ventilation time,NICU residence time and APACHE Ⅱ score after treatment were lower than the control group and the nutritional status index were better than the control group.Meanwhile,the incidence of complications of enteral nutrition such as diarrhea,gastrointestinal bleeding and stress hyperglycemia was relatively low.Moreover,the fatality rate was lower than the control group,but there was no statistical significance.Conclusions:Early application of enteral nutrition support therapy can improve the nutritional status of patients,reduce the incidence of ventilator-associated pneumonia,shorten the time of mechanical ventilation,reduce mortality and improve the prognosis of patients.