The relationship between nutritional status and cognitive function in Alzheimer's disease

VernacularTitle:阿尔茨海默病营养状态与认知功能的相关性研究
Author: Chan-Juan WANG ¹ ; Zheng WANG ; Ling LI ; Yu-Ping MA
Author Information

1. 南京医科大学第一附属医院
Keywords: Alzheimer disease; Malnutrition; Cognitive status
From: Parenteral & Enteral Nutrition 2018;25(1):12-15
CountryChina
Language:Chinese
Abstract: Objective:To investigate the relationship between nutritional status and cognitive function in patients with Alzheimer's disease (AD),and to provide rationale for clinicians in nutrition intervention of AD patients.Methods:Sixty cases of elderly AD patients and 50 cases with normal elderly control were enrolled from the neurological department.Nutritional status and cognitive function were assessed using the laboratory parameters,mini nutritional assessment method (short-form Mini-Nutritional fine assessment,MNA-SF) and MMSE (Mini-Mental State,Examination,MMSE) survey.Results:Compared with control group,the AD group had significantly different laboratory index and MNA-SF score (P ＜ 0.05).MNA-SF scores were positively correlated with MMSE scores in patients with AD (r =0.59,P ＜ 0.05).Conclusion:The incidence of malnutrition in AD patients is high,and it is related to their cognitive function.The nutritional knowledge should be strengthened among doctors and nurses treating patients with AD.