Analysis of clinical features of acute exacerbated chronic obstructive pulmonary disease patients
10.3969/j.issn.1671-8348.2018.16.012
- VernacularTitle:慢性阻塞性肺疾病急性加重患者的临床特征分析
- Author:
Junjun HE
1
;
Yongjun SHEN
;
Yi MENG
;
Lizhu MA
;
Jin LI
;
Heng ZHA
;
Fuqiang WEN
Author Information
1. 四川大学华西医院西藏成办分院呼吸内科
- Keywords:
pulmonary disease,chronic obstructive;
bronchitis,chronic;
pulmonary emphysema;
phenotype;
clinical features
- From:
Chongqing Medicine
2018;47(16):2162-2164
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare clinical characteristics between acute exacerbated chronic obstructive pulmonary disease (AECOPD) patients with chronic bronchitis phenotype and emphysema phenotype.Methods A total of 73 AECOPD patients with chronic bronchitis phenotype and 82 AECOPD patients with emphysema phenotype in Tibet Chengdu Branch Hospital,West China Hospital,Sichuan University from January 2014 to November 2016 were selected.All patients had completed lung function tests,basic information collection,modified medical research council dyspnea scale (MMRC),and COPD assessment test (CAT).The serum samples were collected to detect C-reactive protein (CRP).The clinical characteristics,lung function,complications and systemic inflammation between the two groups were compared.Results There was no difference in body mass index (BMI),CAT score,serum CRP level and length of hospital stay between the AECOPD patients with chronic bronchitis phenotype and emphysema phenotype (P＞0.05).Compared with AECOPD patients with chronic bronchitis phenotype,the AECOPD patients with emphysema phenotype have longer smoking history,higher MMRC score,and more severe lung function impairment (P＜0.05).Conclusion AECOPD patients with chronic bronchitis phenotype and emphysema phenotype have different clinical characteristics,those with emphysema phenotype have more severe dyspnea and lung function impairment.
