Analysis of pathological features and prognosis of T1 invasive ductal breast carcinoma with calcification
10.3969/j.issn.1671-8348.2018.15.012
- VernacularTitle:伴有钙化的T1乳腺浸润性导管癌的病理特征及预后分析
- Author:
Lu DU
1
;
DILIXIATI·Jinsihan
;
Qian ZHAO
;
Wenting XU
;
Dan LI
;
Shuangjian LI
;
Tao WU
;
Liping ZHU
;
Xun LUO
;
Liang YANG
Author Information
1. 新疆医科大学附属肿瘤医院乳腺外科一病区
- Keywords:
T1 breast neoplasm;
calcification;
pathologic features;
prognosis
- From:
Chongqing Medicine
2018;47(15):2020-2023
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the pathological characteristics and prognostic influencing factors of T1 invasive ductal breast carcinoma with calcification.Methods The clinicopathological and follow-up data in 172 patients with initially treated operable T1 invasive ductal breast cancer in this hospital from June 2012 to June 2013 were analyzed restrospectively.The patients were divided into the calcification group and non-calcification group based on the breast X-ray image features.The differences of pathological characteristics between two groups,related factors,and relationship between the calcification expression with patient survival were analyzed.Results The pathological types,lymph node metastasis,Her-2 overexpression,TNM stage and Ki-67 had statistically significant difference between the calcification group and non-calcification group(P<0.05).The multivariate analysis showed that the cases type,lymph node metastasis and Ki-67 were the related risk factors affecting the calcification expression(P<0.05).The 3-year disease-free survival rate in the the calcifi cation group and non-calcification group were 87.30% and 95.06% respectively.The lymph node status and calcification were the independent predictive risk factors affecting the disease-free survival time of invasive ductal breast carcinoma(P<0.05).Conclusion Calcification is visible X-ray risk factor of T1 invasive ductal breast carcinoma prognosis.