Effects of oxycodone hydrochloride combined with propofol on hemodynamics and related indexes in painless fiberoptic bronchoscopy
10.3969/j.issn.1671-8348.2018.14.011
- VernacularTitle:盐酸羟考酮联合丙泊酚应用于无痛纤支镜对血流动力学及相关指标的影响
- Author:
Ke ZHANG
1
;
Tianke XIAO
;
Lei QI
;
Zuqi CHEN
;
Xueying YU
Author Information
1. 成都医学院第二附属医院·核工业416医院麻醉科
- Keywords:
oxycodone hydrochloride;
sufentanil;
propofol;
painless;
fiberoptic bronchoscopy;
hemodynamics
- From:
Chongqing Medicine
2018;47(14):1882-1884
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effects of oxycodone hydrochloride combined with propofol on hemodynamics and related indicators in painless fiberoptic bronchoscopy.Methods Ninety patients receiving fiberoptic bronchoscopic examination from January 2016 to May 2017 were selected and divided into the sufentanil+propofol group(group A) and oxycodone hydrochloride+propofol group(group B) according to the random number table method 45 cases in each group.The hemodynamic indicators,intraoperative propofol dosage and incidence rate of adverse reactions in both groups were observed.Results The respiratory rate(RR) in the bronchoscope reaching the glottis(T2) in the group A was significantly higher than that in the group B (P＜ 0.05);mean arterial pressure(MAP),heart rate(HR),blood oxygen saturation(SpO2) and RR at the bronchoscope passing trachea carina(T3) and examination completing(T4) in the group A were significantly higher than those in the group B(P＜0.05).RR at 10 min after the examination completing(T5) in the group A was significantly higher than that in the group B,the difference was statistically significant(P＜0.05).The propofol dosage in the group A was significantlyhigher than that in the group B(P＜0.05);the incidence rate of adverse reactions in the group A was 31.11％,which was significantly higher than 6.67％ in the group B,the difference was statistically significant(P＜0.05).Conclusion Oxycodone hydrochloride combined with propofol can more stabilizes the change of hemodynamic parameters during the bronchofibroscopic examination process compared with sufentanil combined with propofol and can reduce the propofol dosage and incidence rate of adverse reactions.
