The effect of gestational diabetes mellitus on the newborn metabolism related indexes and prognosis
10.3969/j.issn.1671-8348.2018.13.012
- VernacularTitle:妊娠期糖尿病对新生儿代谢相关指标及预后的影响
- Author:
Yi DENG
1
;
Huamei YANG
;
Weili YANG
;
Zhengrong TANG
;
Feng LEI
;
Li WANG
;
Zhen MENG
;
Yong XIE
;
Weilin OU
Author Information
1. 桂林医学院第二附属医院新生儿科
- Keywords:
diabetes,gestational;
adiponcetin;
insulin;
infant,newborn;
prognosis
- From:
Chongqing Medicine
2018;47(13):1743-1745
- CountryChina
- Language:Chinese
-
Abstract:
Objective Investigate the effect of gestational diabetes mellitus (GDM)on the neonatal metabolism and prognosis.Methods A total of 265 singleton pregnancy GDM patients were collected as the observation group,while 260 cases of healthy singleton pregnant women were chosen as the control group.Detected the levels of adiponectin,insulin,C-peptide,glycated hemoglobin and blood glucose,compared the prognosis of two groups.Results Compared with the control group,adiponcetin and blood glucose in 2 hours after birth in observation group were lower,insulin,C-peptide and glycated hemoglobin were higher,the number of cesarean section was more,the difference was statically significant (P<0.05).The incidence of low birth weight infant,macrosomia,neonatal asphyxia,neonatal hypoglycemia,neonatal hyperbilirubinemia,neonatal pneumonia,fetal death and newborn teratogenesis in the observation group was higher than that in the control group,the difference was statically significant (P<0.05).Conclusion GDM could cause metabolic disorder and affect fetal growth and development,leading to poor prognosis.