Adenovirus detection in 25 602 hospitalized children with respiratory tract infection
10.3969/j.issn.1671-8348.2018.12.023
- VernacularTitle:25602例住院儿童呼吸道腺病毒感染检出分析
- Author:
Heping WANG
1
;
Yuejie ZHENG
;
Haixia ZHAO
;
Jikui DENG
;
Fanghua YANG
;
Xiliang LI
;
Hongmei WANG
Author Information
1. 广东省深圳市儿童医院呼吸科 518038
- Keywords:
respiratory infection;
adenovirus;
hospitalized children;
epidemiology
- From:
Chongqing Medicine
2018;47(12):1661-1663
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the characteristics of adenovirus infection in hospitalized children with respiratory tract infection in Shenzhen.Methods Nasopharyngeal swabs obtained from 25 602 children hospitalized with respiratory tract infections in Shenzhen Children's Hospital during 2014 to 2016,were tested for adenovirus with direct immunofluorescence assay.The detection rate of adenovirus and diagnosis in hospitalized children with respiratory tract infection were analyzed.Results The total adenovirus detection rate was 2.97 ％ in 25 602 samples,with a male to female ratio of 2.04:1,no significantly difference in detection rate in male (3.12％) and female (2.70％).Accounted for 724 (95.14％) of the total adenovirus positive detection children below six years old,and 409(53.75％) children were detected below two years old.There was a distinct seasonality;the detection rate was higher in summer and winter (x2 =36.631,P＜0.01).In 761 hospitalized patients of ADV positive,431 were pneumonia,109 were bronchitis,74 were tonsillitis,14 were conjunctivitis pharynx and 133 were acute upper respiratory infection.Conclusion Our study demonstrates that respiratory adenovirus infection is an important cause of hospitalization in children below the age of 6 years in Shenzhen,China.The detection rate was higher in summer and winter than spring and autumn.Most adenovirus positive children were diagnosed by pneumonia,bronchitis and acute upper respiratory tract infection.
