A Case of Neonatal Hyperthyroidism with Unilateral Ear Anomaly.
- Author:
Kwang Ok CHUNG
1
;
Na Yeon KIM
;
Sung Min CHO
;
Dong Seok LEE
;
Doo Kwun KIM
;
Sung Min CHOI
Author Information
1. Department of Pediatrics, College of Medicine, Dongguk University, Kyongju, Korea.
- Publication Type:Case Report
- Keywords:
Neonatal hyperthyroidism;
Thyroid-stimulating antibody (TSAb);
Ear anomaly
- MeSH:
Diagnosis;
Diarrhea;
Ear Canal;
Ear*;
Exophthalmos;
Female;
Fetus;
Graves Disease;
Humans;
Hyperthyroidism*;
Immunoglobulins, Thyroid-Stimulating;
Infant;
Infant, Newborn;
Mothers;
Propranolol;
Tachycardia;
Tachypnea;
Thyroid Function Tests;
Thyroid Gland;
Thyroiditis
- From:Journal of the Korean Pediatric Society
1998;41(6):845-849
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Neonatal hyperthyroidism is a very rare disorder occurring typically in the offspring of patients with Graves' disease or chronic thyroiditis. It is caused by the transplacental passage of thyroid stimulating antibodies (TSAb) from the mother to the fetus. There has been few reports of neonatal hyperthyroidism associated with congenital anomalies. We experienced a case of neonatal hyperthyroidism with unilateral microtia and agenesis of external auditory canal in a female neonate born to a mother who had euthyroid but with a thyroid stimulating antibody. The patient was presented with unusual alertness, tachycardia, tachypnea, watery diarrhea, periorbital swelling and exophthalmos. Diagnosis was made by thyroid function tests and TSAb. She was treated with Lugol solution, PTU and propranolol. New she is 6 months old and in good condition with no symptoms of hyperthyroidism.
