Effect of bundles intervention for preventing ventilator associated pneumonia:a Meta analysis
10.3969/j.issn.1671-8348.2018.09.024
- VernacularTitle:集束化干预预防呼吸机相关性肺炎效果的Meta分析
- Author:
Xueman RAN
1
;
Jun SHEN
Author Information
1. 重庆医科大学护理学院 400016
- Keywords:
bundles interventions;
ventilator associated pneumonia;
Meta analysis
- From:
Chongqing Medicine
2018;47(9):1225-1228,1232
- CountryChina
- Language:Chinese
-
Abstract:
Objective To assess the effect of the bundles intervention for preventing ventilator-associated pneumonia(VAP) in the mechanically ventilated patients.Methods The clinical controlled trials on the bundles intervention for preventing VAP were retrieved from the databases of CBM,CNKI,VIP,Wanfang Databases,Cochrane library,Embase and PubMed database.The litera-ture screening,quality evaluation and data extract were performed by adopting the Cochrane systematic assessment method.The da-ta were analyzed by adopting the Stata12.0 software.Results Twenty-four articles were included,involving 6 000 patients.The me-ta analysis results verified that the VAP incidence rate in the intervention group was significantly lower than that in the control group(OR=0.39,95% CI:0.34-0.45,Z=12.36,P<0.01);the mortality rate in the intervention group was significantly lower than that in the control group(OR=0.35,95% CI:0.26-0.48,Z=6.43,P<0.01);the duration of mechanical ventilation and ICU stay length in the intervention group were significantly shortened compared with the control group,the effective dose standardized mean difference(SMD)and 95% CI were -0.75,-0.95 - -0.55 and -0.78,-0.98 - -0.53 respectively,the difference was statistically significant(Z=7.35,P<0.01;Z=7.72,P<0.01).Conclusion The bundles intervention can significantly reduce the incidence of VAP,mechanical ventilation time and ICU stay time,it is recommended to be used in clinic.
