Analysis of influential factors in bronchodilation test in mechanically ventilated patients with chronic obstructive pulmonary diseases
10.3969/j.issn.1671-8348.2018.09.015
- VernacularTitle:慢性阻塞性肺疾病机械通气患者支气管扩张试验影响因素分析
- Author:
Hongqun WANG
1
;
Xingsheng WANG
Author Information
1. 重庆市急救医疗中心/重庆市第四人民医院呼吸内科 400014
- Keywords:
chronic obstructive pulmonary diseases;
bronchodilation test;
fungal infection
- From:
Chongqing Medicine
2018;47(9):1197-1199
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the main influential factors of bronchodilation test positive results in mechanically ventila-ted patients with chronic obstructive pulmonary disease(COPD).Methods A total of 55 inpatients with acute exacerbation of COPD(AECOPD)receiving the invasive ventilation from June 2015 to March 2016 were collected.The accurate respiratory mechan-ics monitoring was performed before and after using the bronchodilator.The airway resistance reduction over 12% after inhaling bronchodilator served as the judgment criteria,the patients were divided into the bronchodilation test positive or negative groups, then the influential factors were compared and statistical analysis was performed.Results Twenty-nine cases(52.7%)showed the positive reaction and 26 cases(47.2%)were negative.After univariate analysis,results of heart rate,SaO2,fungal infection,horm-onotherapy,CKMB,lactic acid and BNP were brought into the multivariable Logistic regression analysis(P< 0.1).The analysis found that fungal infection was an independent factor affecting the results of the bronchodilation test(P<0.05).Conclusion Fun-gal infection is an independent influential factor of the bronchodilation test positive in COPD patients receiving invasive ventilation.
