Clinical effect of fire needle in treating vitiligo and its CLSM image characteristics
10.3969/j.issn.1671-8348.2018.09.002
- VernacularTitle:火针治疗稳定期白癜风的临床疗效及其CLSM图像特点
- Author:
Yuyi WANG
1
;
Qingchun DIAO
;
Chunzhu NING
;
Xin WEN
;
Yin YU
;
Wei XU
;
Chunrong TAO
Author Information
1. 重庆市中医院/重庆市第一人民医院皮肤科 400011
- Keywords:
fire needle;
vitiligo;
confocal laser scanning microscopy
- From:
Chongqing Medicine
2018;47(9):1155-1157
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the clinical effect of fire needle in treating vitiligo and the characteristics of vitiligo image by the confocal laser scanning microscope(CLSM).Methods The randomized self-controlled experiment design was adopted.Each patient selected two symmetric or adjacent white patches and randomly received the fire needle treatment or tacrolimus treatment. The duration of treatment was 3 months.The CLSM images of white patches were recorded before treatment and after 3,6 times of fire needle treatment.Results Among 41 cases of stable stage vitiligo,The effective rates of the fire needle group and tacrolimus group were 82.9% and 78.0% respectively,and the difference was not statistically significant(P>0.05).After fire needle treat-ment,dentritic melanin cells appeared,the pigment granules gradually appeared around the basal layer and corpora papillare,and formed the pigment ring.Conclusion Fire needle and tacrolimus have the similar effect in treating vitiligo,moreover CLSM can be used as the non-invasive,objective and reliable detection means of the recovery of vitiligo melanocyte.
