Analysis on correlation between DWI in diagnosis of prostate cancer and Gleason score
10.3969/j.issn.1671-8348.2018.06.015
- VernacularTitle:DWI对前列腺癌诊断与Gleason评分的相关性分析
- Author:
Yong LIU
1
;
Zhengyu SONG
;
Liulu ZHANG
;
Zhengjun CHEN
Author Information
1. 西南医科大学附属中医医院MRI室
- Keywords:
prostate neoplasms;
diffusion weighted imaging;
Gleason score
- From:
Chongqing Medicine
2018;47(6):770-772
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the correlation between the detection rate of diffusion weighted imaging(DWI) in diagnosis prostate cancer and the Gleason score.Methods Ninety-one cases of intact pathological data and clinically suspected prostate cancer were collected.All cases were undertaken the routine sequence (TIWI/T2WI) and DWI (value b=600 s/mm2) examination.The cases of pathologically diagnosed prostate cancer were performed the Gleason score.Results Among 91 cases,44 cases were benign prostatic hyperplasia(BPH) and 47 cases were prostate carcinoma(PCa).The ADC values in the BPH group and PCa group were (1.250±0.263)× 10-3mm2/s and (0.955±0.191)× 10-3mm2/s.According to Gleason score,the PCa group was re-divided into three sub-groups:high differentiation,middle differentiation and low differentiation,the apparent diffusion coefficient(ADC) values were (1.158±0.173)× 10-3mm2/s,(1.050±0.192)× 10-3mm2/s and (0.891±0.241) × 10-3 mm2/s respectively.Their diagnostic accuracy rates for diagnosing PCa were 63.6%,78.3% and 84.6% respectively.The ADC value of different pathological groups in PCa with Gleason score is negatively correlated with the Gleason score.The accuracy rate of DWI in diagnosis of PEa is positively correlated with the Gleason score.Conclusion The lower prostate cancer differentiation,the higher Gleason score and the higher accuracy of DWI in diagnosing PCa.