Target organs function damage in elderly patients with H type hypertension and its association with blood pressure variability
10.3969/j.issn.1671-8348.2018.06.006
- VernacularTitle:老年H型高血压患者靶器官功能损伤及其与血压变异性的关联性
- Author:
Yuhong MA
1
;
Fuhou CHANG
;
Tuya BAI
;
Weizhong HUANGPU
Author Information
1. 内蒙古医科大学附属医院老年病科
- Keywords:
old age;
H type hypertension;
blood pressure variability;
target organ
- From:
Chongqing Medicine
2018;47(6):740-743,747
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the target organs function damage in elderly patients with H type hypertension and its association with blood pressure variability.Methods Ninety-two patients with H type hypertension in the Affiliated Hospital of Inner Mongolia Medical University from January 2014 to January 2016 were collected as the observation group and contemporaneous 135 elderly patients with non-H type hypertension were collected as the control group.The main observation indicators included 24 h systolic/diastolic blood pressure variability,24 h average systolic/diastolic blood pressure,glomerular filtration rate(GFR),serum creatinine,24 h urinary microalbumin,carotid intima-media thickness and left ventricular mass index.Results Compared with the control group,24 h systolic blood pressure variability,24 h diastolic blood pressure variability,creatinine,24 h urinary microalbumin,carotid intima-media thickness and left ventricular mass index in the observation group were significantly increased(P＜0.05);GFR was significantly decreased (P＜0.05).The multiple linear regression analysis showed that 24 h systolic blood pressure variability was the factors affecting GFR (P＜0.05);24 h systolic blood pressure variability was the factor affecting~the creatinine level (P＜0.05);24 h systolic blood pressure,24 h systolic blood pressure variability and 24 h diastolic blood pressure variability were the influence factors of carotid intima-media thickness (P＜0.05);24 h systolic blood pressure variability was the influence factor of left ventricular mass index (P＜0.05).Conclusion The target organs function damage in the patients with H type hypertension is serious,and the blood pressurevariability enlargement is the influencing factor of target organs function damage.
