Study on correlationship between fasting blood glucose level and coronary arterial vulnerable plaque in civil airline pilots
10.3969/j.issn.1671-8348.2018.05.022
- VernacularTitle:民航飞行员空腹血糖水平与冠状动脉易损斑块的相关性研究
- Author:
Zeyuan FAN
1
;
Hanhua JI
Author Information
1. 民航总医院心内科
- Keywords:
civil airline pilots;
fasting blood glucose;
coronary artery disease;
vulnerable plaque
- From:
Chongqing Medicine
2018;47(5):647-649,653
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relationship between fasting blood glucose(FBG) with coronary arterial vulnerable plaque in civil airline pilots and its risk factors.Methods One hundred and twenty civil airline pilots with coronary heart disease were divided into the vulnerable plaque group and non-vulnerable plaque group based on the virtual histology intravascular ultrasound(VH-IVUS) results.Then the clinical data were collected.Logistic regression analysis was used to analyze the risk factors of vulnerable plaque.Results The FBG level in the vulnerable plaque group was much higher(P＜0.05);FBG,high-sensitivity C-reactive protein and low density lipoprotein were the risk factors for vulnerable plaque;FBG was positively correlated with the plaque necrosis core constituent ratio(r=0.44,P＜0.05).The area under curve of ROC curve efficiency for diagnosing vulnerable plaque was 0.72(95％CI:0.66-0.81),at FBG cut-off value of 6.39,the sensitivity was 71.35％ and specificity was 76.15％.Conclusion The FBG level is an independent risk factor of coronary arterial vulnerable plaque,which can assist in the identification of vulnerable plaque in civil airline pilots.
